Non-Human Primate Chemogenetics

Over the last decade, molecular tools have emerged as a valuable approach to asking questions in the field of systems neuroscience. Chemogenetic techniques, such as DREADDs, have been successfully applied in various areas of rodent research. However, application to NHP research has lagged behind. This is in part due to the impracticality of producing germ-line modifications in the NHP species most commonly found in the laboratory (such as Macaques), and in part due to the cost and time required to optimize transmission of genetic material via viral vectors. The goal of this private forum is allow researchers attempting to apply chemogenetic technology in NHPs to exchange advice and share preliminary data in a confidential setting. By registering to access this forum, users agree not to reproduce any content found herein without the express written permission of the original contributor.